Makhzoumi Foundation primary healthcare center is assigned as a mental health community center in a pilot study that is ongoing. As such, it provides through the Ministry of Public Health a list of mental and neurological medications free of charge to its community members based on specialized physician’s prescriptions. To improve the prescribing habits of those medications, the National Mental Health Program at the Ministry of Public Health in collaboration with the World Health Organization organized orientation sessions for psychiatrists, neurologists and clinical pharmacists to launch the “Guide for the rational prescription of medications for priority mental and neurological conditions for specialists in the public health system”. This guide advocates for the rational medication prescription and provides contextualized evidence-based pharmacological treatment to improve quality of prescription.